Education
1996 |
PhD Simon Fraser University, Canada |
1992 |
MSc University of British Columbia, Canada |
1984 |
BSc South China Agricultural University, China |
Position
8.2007-present |
Professor (Department of Biology, The Chinese University of Hong Kong, Hong Kong) |
8.2004-7.2007 |
Associate Professor (Dept of Biology, The Chinese University of Hong Kong, Hong Kong) |
8.2000-7.2004 |
Assistant Professor (Dept of Biology, The Chinese University of Hong Kong, Hong Kong) |
1996-2000 |
Research Associate (Institute of Biological Chemistry, Washington State University, USA) |
Membership in the following Professional Organizations
The American Society for Plant Biologists |
The American Association for the Advancement of Science |
The International Society for Seed Science |
Research Interest
1. Plant cell biology and molecular biology |
2. Protein targeting and organelle biogenesis |
3. Molecular characterization of plant prevacuolar compartments |
4. Molecular mechanism of protein degradation in germinating seeds |
5. Plant biotechnolog |
Representative Publications (* indicates PI and Corresponding Author)
1. |
Miao, Y.S. and *Jiang, L. (2007) Transient expression of fluorescent fusion proteins in protoplasts of suspension cultured cells. Nature Protocols 2: 2348-2353. |
2. |
Lam, S.K., Tse, Y.C., Robinson, D.G and *Jiang, L. (2007) Tracking down the elusive early endosome. Trends in Plant Science 12: 497-505. |
3. |
Wang, J.Q., Li, Y.B., Lo, S.W., Hillmer, H., Sun, S.S.M., Robinson, D.G. and *Jiang, L. (2007) Protein mobilization in germinating mung bean seeds involves vacuolar sorting receptors and multivesicular bodies. Plant Physiology 143: 1628-1639. |
4. |
Lam, S.K., Siu, C.L., Hillmer, S., Jang, S., An, G., Robinson, D.G. and *Jiang, L. (2007) Rice SCAMP1 defines clathrin-coated, trans Golgi-located tubular vesicular structures as an early endosome in tobacco BY-2 cells. The Plant Cell 19: 296-319. |
5. |
Tse, Y.C., Lo, S.W., Hillmer, S., Dupree, P. and *Jiang, L. (2006) Dynamic response of prevacuolar compartments to Brefeldin A in plant cells. Plant Physiology 142: 1442-1459. |
6. |
Miao, Y., Yan, P.K., Kim, H., Hwang, I. and *Jiang, L. (2006) Localization of GFP fusions with the seven Arabidopsis vacuolar sorting receptors to prevacuolar compartments in tobacco BY-2 cells. Plant Physiology 142: 945-962. |
7. |
Mo, B.X., Tse, Y.C. and *Jiang, L. (2006) Plant prevacuolar/endosomal compartments. International Review of Cytology 253: 95-129. (cover article) |
8. |
Oliviusson, P., Heinzerling, L., Hillmer, S., Hinz, G., Tse, Y.C., Jiang, L. and Robinson, D.G. (2006) Plant retromer: localized to the prevacuolar compartment and microvesicles in Arabidopsis, may interact with vacuolar sorting receptors. The Plant Cell 18: 1239-1252. |
9. |
Wang, J.Q., Miao, Y.S. and *Jiang, L. (2006) Response to Gomord et al: Golgi-bypassing delivery of biopharmaceutical proteins to protein storage vacuole in plant bioreactors. Trends in Biotechnology 24: 147-149. |
10. |
Lo, S.W. and *Jiang, L (2006) Molecular study of prevacuolar compartments in tobacco BY-2 cells. Biotechnology in Agriculture and Forestry 58: 153-166. |
11. |
Oufattole, M., Park, J.H., Poxleitner, M., *Jiang, L and Rogers, J.C. (2005) Selective membrane protein internalization accompanies movement from ER to protein storage vacuole. The Plant Cell 17: 3066-3080. |
12. |
Lam, S.K., Tse, Y.C., Jiang, L , Oliviusson, P., Heinzerling, L., and Robinson, D.R. (2005) Plant prevacuolar compartments and endocytosis. Plant Cell Monographs 1: 37-61. |
13. |
Tse, Y.C., Mo, B.X., Hillmer, S., Zhao,M., Lo, S.W., Robinson, D.G., and *Jiang, L (2004) Identification of multivescular bodies as prevacuolar compartments in Nicotiana tabacum BY-2 cells. The Plant Cell 16: 672-693. |
14. |
Jin, J.B., Bae,H., Kim, S.J., Go, C., Kim,D.H., Lee, Y.J., Tse, Y.C., Jiang, L and Hwang, I. (2003) Arabidopsis dynamin-like proteins, ADL1C and ADL1E, play a critical role in mitochondrial morphogenesis. The Plant Cell 15: 2357-2369. |
15. |
Mo, B.X., Tse, Y.C. and *Jiang, L. (2003) Organelle identification and proteomics in plant cells. Trends in Biotechnology 21: 331-332. |
16. |
Sohn, E.S., Kim, E.S., Zhao, M., Kim, S.J., Kim, H.R., Kim, Y.W., Lee, Y.J., Hillmer, S., Sohn, U., Jiang, L., and Hwang, I. (2003) Rha1, an Arabidopsis Rab5 homolog, plays a critical role in the vacuolar trafficking of soluble cargo proteins. The Plant Cell 15:1057-1070. |
17. |
*Jiang, L. and Rogers, J.C. (2003) Sorting of lytic enzymes in the plant Golgi apparatus. Annual Plant Review 9: 114-140. |
18. |
Jiang, L., Erickson, A. and Rogers, J.C. (2002) Multivesicular bodies: a mechanism to package lytic and storage function in one organelle? Trends in Cell Biology 12: 362-367. |
19. |
Li, Y.B., Rogers, S.W., Tse, Y.C., Lo, S.W., Sun, S.S.M., Jauh, G.Y. and *Jiang, L. (2002) BP-80 and homologs are concentrated on post-Golgi, probable lytic prevacuolar compartments. Plant & Cell Physiology 43: 726-742. |
20. |
*Jiang, L. and Sun, S.S.M. (2002) Membrane anchors for vacuolar targeting: application in plant bioreactors. Trends in Biotechnology 20: 99-102. (cover article) |
21. |
Jiang, L., Phillips, T.E., Hamm, C.A., Drozdowicz, Y.M., Rea, P.A., Maeshima, M., Rogers, S.W. and Rogers, J.C. (2001) The protein storage vacuole: a unique compound organelle. The Journal of Cell Biology 155: 991-1002. (journal highlight article) |
22. |
Jiang, L., Phillips, T.E., Rogers, S.W. and Rogers, J.C. (2000) Biogenesis of the protein storage vacuole crystalloid. The Journal of Cell Biology 150: 755-769. |
23. |
Jiang, L. and Rogers, J.C. (1999) Functional analysis of a Golgi-localized Kex2p-like protease in tobacco suspension culture cells. The Plant Journal 18: 23-32. |
24. |
Jiang, L. and Rogers, J.C. (1998) Integral membrane protein sorting to vacuoles in plant cells: evidence for two pathways. The Journal of Cell Biology 143: 1183-1199. (this article was featured in Trends in Cell Biology) |
Research Grants
Research Grants Council (RGC) Earmarked Grants |
2008-2010 |
Molecular characterization of plant endocytosis - HK$1,408,404 (as PI) |
2006-2008 |
The biology of vacuolar sorting receptor proteins and their applications in plant bioreactors - HK$1,446,465 (as Co-PI, PI, Prof. SSM Sun) |
2003-2008 |
Biogenesis of the compound protein storage vacuole - HK$2,394,000 (as PI) |
2002-2005 |
Molecular characterization of plant prevacuolar compartments - HK$1,387,580 (as PI) |
2001-2004 |
Sorting of proteins to the protein storgae vacuole in plant cells - HK$1,154,000 (as PI, Co-I, Prof SSM Sun) |
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CUHK Scheme C |
2006-2009 |
Molecular characterization of plant prevacuolar compartments - HK$1,086,000 (as PI) |
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National Nature Science Foundation of China (NSFC) |
2006-2008 |
Biogenesis of protein storage vacuole and its application - RMB$400,000 (as PI; collaborator, Prof. ZF Xu) |
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The National High Technology Research and Development Program of China (863 Program) |
2008-2010 |
Plant cells as bioreactors for pharmaceuticals - RMB$1,000,000 (50% of the fund as Co-I; PI, Prof. ZF Xu) |
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France / Hong Kong Joint Research Scheme |
2003-2004 |
Molecular mechanism of plant prevacuolar compartments - HK$63,000 |
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Gemany / Hong Kong Joint Research Scheme |
2002-2003 |
Protein sorting in the plant Golgi - HK$60,000 |
2007-2008 |
Structural characterization and proteomics of plant prevacuolar compartments - HK$60,000 |
Awards
2009-10 |
The Prestigious Senior Research Fellowship of The Croucher Foundation |
2008 |
Exemplary Teaching Award, Faculty of Science, The Chinese University of Hong Kong |
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