Selected Publication

[1] Yishan LUO, Lin SHI, Jian WENG, Hongjian HE,  Winnie CW CHU, Feiyan CHEN, Defeng WANG*, Intensity and Sucli Landmark Combined Brain Atlas Construction for Chinese Pediatric Population, Human Brain Mapping 2014 Aug;35(8):3880-92 (SCI IF: 6.878)

[2] Defeng Wang, Lin Shi, Winnie C.W. Chu, R. Geoffrey Burwell, Jack C.Y. Cheng, Anil T. Ahuja. Abnormal cerebral cortical thinning pattern in adolescent girls with idiopathic scoliosis, NeuroImage 2012, 59(2):935-42 (SCI 5-year IF: 6.884).

[3] Lin Shi, Defeng Wang*, Winnie C.W. Chu, Tien-Tsin Wong, Geoffrey R. Burwell, and Jack C.Y. Cheng, Pheng Ann Heng. Automatic MRI segmentation and morphoanatomy analysis of the vestibular system in adolescent idiopathic scoliosis, NeuroImage 2011;54 Suppl 1:S180-8. (SCI 5-year IF: 6.884)

[4] Defeng Wang, Lin Shi, Yi-Xiang J. Wang, Jing Yuan, David Yeung, Ann D. King, Anil T. Ahuja, and Pheng Ann Heng, Concatenated and Parallel Optimization for the Estimation of T1 Map in FLASH MRI with Multiple Flip Angles, Magnetic Resonance in Medicine, 63(5):1431 – 1436, 2010 (SCI 5-year IF: 4.163)

[5] Huisi Wu, Wen-Xiang Yuan, Xiaojin Zhao, Lin Shi, Defeng Wang, Calculation of incompressible left ventricular torsion using cardiovascular magnetic resonance, International Journal of Cardiology ( DOI: 10.1016/j.ijcard.2014.07.119, In press) (SCI IF: 6. 175)

[6] Defeng Wang, Youyong Kong, Winnie CW Chu, Cindy WC Tam, Linda CW Lam, Yilong Wang, Georg Northoff, Vincent CT Mok, Yongjun Wang, Lin Shi, Generation of the Probabilistic Template of Default Mode Network Derived from Resting-State fMRI, IEEE Transactions on Biomedical Engineering 2014 May 16. (SCI IF: 2.348)

[7] Chan CCK, Shi L, So HK, Wang D, Liew AWC, Rasalkar DD, Chu CW, Wing YK, Li AM, Neurocognitive Dysfunction and Grey Matter Density Deficit in Children with Obstructive Sleep Apnoea, Sleep Medicine 2014 June 09 (to appear, SCI: 3.49)

[8] Ryan Wen Liu, Lin Shi, Wenhua Huang, Jing Xu, Simon Chun Ho Yu, Defeng Wang, Generalized total variation-based MRI rician denoising model with spatially adaptive regularization parameters. Magnetic Resonance Imaging, July 2014, 32(6):702–720 (IF: 2.286)

[9] Chen YK, Mok V, Wang D, Shi L, Chu WCW, Wong KS, Ungvari GS, Liu XX, Tang WK. Hippocampal and amygdala size in patients with ischemic stroke: does small vessel disease play a role? Journal of Neurophysiology and Neurological Disorders March 18, 2014, 1:1-6

[10] Minqi Zhang, Fang Li, Xingce Wang, Zhongke Wu, Shi-Qing Xin, Lok-Ming Lui, Lin Shi, Defeng Wang, Ying He. Automatic Registration of Vestibular Systems with Exact Landmark Correspondence. Graphical Models, Volume 76, Issue 5, September 2014, Pages 532–541 (SCI: 0.6)

[11] LEUNG Ling Yan; CHAN Pui Yee Cangel; LEUNG Yuk Ki; JIANG Hui Lin; ABRIGO Jill Morales; WANG Defeng; CHUNG Joseph Shun Hang; RAINER Timothy Hudson and GRAHAM C A.  Comparison of miR-124-3p and miR-16 for Early Diagnosis of Hemorrhagic and Ischemic Stroke.  Clinica Chimica Acta vol.433 pp.139–144. 2014.06. (SCI: 2.67)

[12] Huisi Wu, Defeng Wang, Lin Shi, Zhiqiang Wang, Zhong Ming. Midsagittal plane extraction from brain images based on 3D SIFT, Medical Engineering & Physics 2014 Mar 21;59(6):1367-87 (SCI IF: 2.26)

[13] Youyong Kong, Lin Shi, Defeng Wang*, Min Deng, Steve CN Hui, Jack CY Cheng, Winnie CW Chu. Variation in Anisotropy and Diffusivity along Medulla Oblongata and the Whole Spinal Cord in Adolescent Idiopathic Scoliosis: A Pilot Study Using Diffusion Tensor Imaging. American Journal of Neuroradiology, 2014 Apr 30. (SCI IF: 3.010)

[14] Kong Y, Wang D*, Shi L, Hui SCN, Chu WCW, Adaptive Distance Metric Learning for Diffusion Tensor Image Segmentation. PLoS ONE 2014 9(3): e92069. doi:10.1371(SCI IF: 3.730)

[15] Defeng Wang, Lin Shi, Shangping Liu, Steve CN Hui, Yongjun Wang, Jack CY Cheng, Winnie CW Chu. Altered Topological Organization of Cortical Network in Adolescent Girls with Idiopathic Scoliosis. Plos One 2013 8(12): e83767 (SCI IF: 3.730)

[16] Lin Shi, Defeng Wang*, Winnie CW Chu, Shangping Liu, Yunyun Xiong, Yilong Wang, Yongjun Wang, Lawrence KS Wong, Vincent CT Mok. Abnormal Organization of White Matter Network in Patients with no Dementia after Ischemic Stroke. Plos One 2013 8(12): e81388. (SCI IF: 3.730)

[17] Lin Shi, Defeng Wang*, Steve CN Hui, Michael CF Tong, Jack CY Cheng, Winnie CW Chu. Volumetric Changes in Cerebella Regions in Adolescent Idiopathic Scoliosis as Compared with Healthy Controls. Spine Journal 2013 13(12):1904-11 (SCI IF: 3.290)

[18] Lin Shi, Defeng Wang*, Wen Liu, Kui Fang, Yi-Xiang J. Wang, Wenhua Huang, Ann D. King, Pheng Ann Heng, and Anil T. Ahuja,  Automatic Detection of Arterial Input Function in Dynamic Contrast Enhanced MRI Based on Affinity Propagation Clustering, Journal of Magnetic Resonance Imaging, 2014 39:1327-37 (SCI 5-year IF: 3.041) (cover page)

[19] Lin Shi, James F. Griffith, Junbin Huang, Defeng Wang*, Excellent side-to side symmetry in glenoid size and shape. Skeletal Radiology, December 2013, 42 (12): 1711-1715, (SCI IF: 1.741)

[20] Defeng Wang, Steve CN Hui, Lin Shi, Wen-hua Huang, Tianfu Wang, Vincent CT Mok, Winnie CW Chu, Anil T Ahuja, Application of Multimodal MR Imaging on Studying Alzheimer's Disease: A Survey, Current Alzheimer Research. 2013 Oct;10(8):877-92 (SCI IF: 3.96)

[21] Wong A, Xiong YY, Wang D, Shi L, Chu WCW, Kwan P, Nyenhuis D, Black SE, Wong KSL, Mok V. The NINDS-Canadian Stroke Network Vascular Cognitive Impairment Neuropsychology Protocols in Chinese. Journal of Neurology, Neurosurgery and Psychiatry. 2013 May;84(5):499-504 ( SCI IF: 4.77)

[22] Lin Shi, Defeng Wang*, Yuehua Pu , Shangping Liu, Yilong Wang, Winnie Chu, Anil Ahuja , Yongjun Wang,  Automated Quantification of White Matter Lesion in Magnetic Resonance Imaging of Patients with Acute Infarction, Journal of Neuroscience Methods. Volume 213, Issue 1, 15 February 2013, Pages 138–146, (SCI IF: 2.1)

[23] Lin Shi, Wen Liu, Heye Zhang, Yongming Xie, Defeng Wang*. A survey of GPU-based medical image computing techniques. Quantitative Imaging in Medicine and Surgery. Vol 2, No 3. 2012

[24] Wang D, Kong Y, Shi L, Ahuja AT, Cheng JCY, Chu WCW. Fully Automatic Stitching of Diffusion Tensor Images in Spinal Cord. Journal of Neuroscience Methods. 2012, 209(2):371-378 (SCI IF: 2.1)

[25] Lin Shi, Shangping Liu, Defeng Wang*, Hing-lok Wong, Wen-hua Huang, Yi-Xiang J. Wang, James F. Griffith, Ping-chung Leung, Anil T. Ahuja. Computerized Quantification of Bone Tissue and Marrow in Stained Microscopic Images. Cytometry: Part A. 2012 ;81(10):916-21 (SCI 5-year IF: 3.79) (cover page)

[26] Defeng Wang, Lin Shi, James F. Griffith, Ling Qin, David TW Yew, Christopher M Riggs. Comprehensive Surface-Based Morphometry Reveals the Association of Fracture Risk and Bone Geometry. Journal of Orthopaedic Research 2012 Aug;30(8):1277-84 (SCI 5-year IF: 3.385)

[27] Hongluan Yu, Qi Li, Defeng Wang, Lin Shi, Gang Lu, Lin Sun, Li Wang, Wei Zhu, Ying T. Make, Naikei Wong, Yixiang Wang, Fang Pan. Mapping the central effects of chronic ketamine administration in an adolescent primate model by functional magnetic resonance imaging (fMRI). Neurotoxicology 33(1):70–77, 2012 (SCI IF 3.096)

[28] Chu WCW, Wu JCY, Yew DTW, Zhang L, Shi L, Yeung DKW, Wang D, Tong RKY, Chan YW, Lao LX, Leung PC, Berman BM, Sung JJY. Does Acupuncture Therapy Alter Activation of Neural Pathway for Pain Perception in Irritable Bowel Syndrome – A Comparative Study of True and Sham Acupuncture Using Functional MRI. Journal of Neurogastroenterology and Motility 2012 Jul;18(3):305-16 (IF: 3.349)

[29] Vincent Mok, D. Ding, J. Fu, Y. Xiong, WCW Chu, Defeng Wang, J. Yang, JM Abrigo, A. Wong, Q. Zhao, Q. Guo, Z. Hong, KS Wong, Transcranial Doppler Ultrasound for Screening Cerebral Small Vessel Disease – A Community Study, Stroke 2012 Oct;43(10):2791-3 (SCI IF: 5.756)

[30] Miao Hu, Winnie Chiu Wing Chu, Shizuya Yamashita, David Ka Wai Yeung, Lin Shi, Defeng Wang, Daisaku Masuda, Yaling Yang, Brian Tomlinson, Liver fat reduction with niacin is influenced by DGAT-2 polymorphisms in hypertriglyceridaemic patients, Journal of Lipid Research 2012 Apr;53(4):802-9 (IF: 4.92)

[31] X. Qiu, L. Shi, P. Tony, P. Alain, and Defeng Wang, “Atlas-guided Correction of Brain Histology Distortion,” Journal of Pathology Informatics, 2011 2(2):1-7.

[32] Defeng Wang, Lin Shi, Yi-Xiang J. Wang, Gene Chi-Wai Man, Pheng Ann Heng, James F. Griffith, Anil T. Ahuja. Color Quantification for Evaluation of the Stained Tissues. Cytometry: Part A 2011;79(4):311-6 (SCI 5-year IF: 3.79) (cover page)

[33] Lin Shi, Defeng Wang*, Benson HY Yeung, Winnie CW Chu, James F. Griffith, Pheng Ann Heng, Jack CY Cheng. A novel statistical morphometry imaging method for differentiating long bone geometry: methodological development and application with adolescent idiopathic scoliosis (AIS) patients. Medical Engineering & Physics 33 (2011), pp. 1103-1107 (SCI 5-year IF: 1.886)  

[34] Lin Shi, Defeng Wang*, Christopher M Riggs, Ling Qin, James F Griffith. Statistical Analysis of Bone Mineral Density Using Voxel-Based Morphometry ---  An Application on Proximal Sesamoid Bones in Racehorses. Journal of Orthopaedic Research 2011; 29(8):1230-6 (SCI 5-year IF: 3.385)

[35] Lin Shi, Defeng Wang, Mark Driscoll, Winnie CW Chu, Isabelle Villemure, Jack CY Cheng, Carl-Eric Aubin, Biomechanical analysis and modeling of different vertebral growth patterns in adolescent idiopathic scoliosis and healthy subjects, Scoliosis 2011, 6:11. (IF: 1.31)

[36] Yi-Xiang J. Wang, Thibault Quercy-Jouvet, Hao-Hao Wang, Ak-Wai Li, Chun-Pong Chak, Shouhu Xuan, Lin Shi, De-Feng Wang, Siu-Fung Lee, Ping-Chung Leung, Clara B. S. Lau, Kwok-Pui Fung and Ken Cham-Fai Leung. Efficacy and Durability in Direct Labeling of Mesenchymal Stem Cells Using Ultrasmall Superparamagnetic Iron Oxide Nanoparticles with Organosilica, Dextran, and PEG Coatings. Materials 2011, 4(4), 703-715;

[37] Chu WCW, Wang D, Shi L, Rasalkar DD, Heng PA, Cheng JCY. "Difference in Shape and Relative Alignment of Semicircular Canals in Adolescent Idiopathic Scoliosis (AIS) Comparing with Normal Controls: High Resolution MR Imaging and Morphometry Study". Pediatric Radiology 2011,vol.41 no.Suppl 1, pp.S299. (SCI 5-yaer IF: 1.364)

[38] Defeng Wang, Lin Shi, Winnie C.W. Chu, Tomas Paus, Jack C.Y. Cheng, and Pheng Ann Heng, A Comparison of Morphometric Techniques for Studying the Shape of the Corpus Callosum in Adolescent Idiopathic Scoliosis, NeuroImage 2009, 45:738-748 (SCI 5-year IF: 6.884).

[39] Defeng Wang, Lin Shi, Winnie C.W. Chu, Jack C.Y. Cheng, and Pheng Ann Heng, Segmentation of Human Skull in Magnetic Resonance Imaging (MRI) Using Statistical Shape Information from CT Data, Journal of Magnetic Resonance Imaging 2009, 30:490-498 (SCI 5-year IF: 3.041)

[40] Lin Shi, Defeng Wang*, Vivian WY Hung, Benson H.Y. Yeung, James Griffith, Winnie CW Chu, Pheng Ann Heng, Jack CY Cheng, Ling Qin, Fast and Robust 3-D Registration of HR-pQCT Images, IEEE Trans. on Information Technology in BioMedicine,2010, 14(5):1291-7. (SCI 5-year IF: 2.852)

[41] Lin Shi, Defeng Wang*, WCW Chu, R.G. Burwell, B.J.C. Freeman, P.A. Heng, and J.C.Y. Cheng, Magnetic Resonance Morphometric Study of Brain Tissue Densities in Adolescent Idiopathic Scoliosis (AIS) and Normal Controls, American Journal of Neuroradiology 2009, 30:1302-1307 (SCI 5-year IF: 3.010)

[42] Lin Shi, Defeng Wang, Winnie CW Chu, and Jack CY Cheng, Response to article: Adolescent idiopathic scoliosis may not be associated with brain abnormalities, Acta Radiologica, 51(6):711, 2010 (SCI 5-year IF: 1.298)

[43] Defeng Wang, Lin Shi, Pheng Ann Heng, Automatic detection of breast cancers in mammograms using structured support vector machine, Neurocomputing 2009, 72(13-15):3296-3302 (SCI 5-year IF: 1.219)

[44] YX Wang, KCF Leung, WH Cheung, HH Wang, L Shi, Defeng Wang, L Qin, AT Ahuja, Low-intensity pulsed ultrasound increases cellular uptake of superparamagnetic iron oxide nanomaterial: results from human osteosarcoma cell line U2OS. Journal of Magnetic Resonance Imaging 31:1508–1513 (2010) (SCI 5-year IF: 3.041)

[45] D Rasalkar, WCW Chu, KL Cheung, DK Yeung, L Shi, D Wang, PC Ng, AT Ahuja, Magnetic resonance changes with spectroscopy and diffusion tensor imaging after acute cyanide poisoning in a child, European Journal of Radiology Extra 73(e5-e8), 2010

[46] Lin Shi, Defeng Wang, Pheng Ann Heng, TT Wong, CW Chu, HY Yeung, and JCY Cheng, Discriminative Analysis of Skull Morphology in Adolescent Idiopathic Scoliosis Patients: Comparative Study with Normal Controls, Pattern Recognition, 2008, 41(9): 2800-2811, (SCI 5-yaer IF: 3.725)

[47] Chu WC, Luk SS, Wang D, Shi L, Yeung DK, Waye M, Cheng PW, Ahuja AT. Functional MRI findings in Chinese (non-aophabetic) reading dyslexic children: what is different from alphabetic-language dyslexics? Pediatr Radiol 2009:39, S522 (SCI 5-yaer IF: 1.364)

[48] W Chu, D Wang, B Freeman, G Burwell, T Paus, GCW Man, A Cheng, HY Yeung, KM Lee, and J Cheng, Evaluation Of Brain Morphometry In Girls With Adolescent Idiopathic Scoliosis (AIS): A Comparison With Age And Sex-Matched Controls, Journal of Bone and Joint Surgery, British volume Vol 91-B, Issue SUPP_III, 429 (SCI 5-yaer IF: 2.837)

[49] Defeng Wang, Lin Shi, Selecting Valuable Training Samples for SVMs via Data Structure Analysis, Neurocomputing, 2008, 71: 2772-2781 (SCI 5-year IF: 1.219)

[50] D.S. Yeung, Defeng Wang*, Wing W. Y. Ng, Eric, C. C. Tsang, and X Wang, Structured Large Margin Machine: Sensitive to Data Distribution, Machine Learning, 2007, 68(2): 171-200 (SCI 5-year IF: 4.254)

[51] Defeng Wang, Daniel S. Yeung, and Eric C.C. Tsang, Structured one class classification, IEEE Transactions on System, Man and Cybernetics, part B. 2006, 36(6): 1283-1295, (SCI 5-year IF: 2.992)

[52] Defeng Wang, Daniel S. Yeung, and Eric C.C. Tsang, Weighted Mahalanobis Distance Kernels for Support Vector Machines, IEEE Transaction on Neural Networks. 2007,18(5):1453-1462 (SCI 5-year IF: 4.144)

[53] Defeng Wang, Lin Shi, Daniel S. Yeung, Eric C.C. Tsang, and Pheng Ann Heng, Ellipsoidal Support Vector Clustering for Functional MRI Analysis, Pattern Recognition. 2007, 40(10):2685-2695 (SCI 5-yaer IF: 3.725)

[54] Daniel S. Yeung, Wing W.Y. Ng, Defeng Wang, Eric C.C. Tsang and XiZhao Wang, Localized Generalization Error and Its Application to Architecture Selection for Radial Basis Function Neural Network, IEEE Transaction on Neural Networks. 2007, 18(5): 1294-1305. (SCI 5-year IF: 4.144)

[55] Defeng Wang, Shi Lin, Pheng Ann Heng, Radial Thickness Calculation and Visualization for Volumetric Layers, Insight Journal, Issue 8, 2007.