Dr Huina Zhang

Postdoctoral Research Fellow (2012-2014) Institute of Vascular Medicine and School of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong, China

The Associate Professor (2015-2018) and currently the Professor (January 2019 -) at An Zhen Hospital, Capital Medical University and Key Laboratory of Upper Airway Dysfunction-related Cardiovascular Diseases, Beijing Institute of Heart Lung and Blood Vessel Disease, Beijing, China

• Zhang H, Dong J, Lau CW, Wei Y & Huang Y (2022) Berberine reverses nitroglycerin tolerance through suppressing PKCα activity in vascular smooth muscle cells. Cardiovascular Drugs and Therapy 36(4):633-643

• Zhang H, Peng L, Wang Y, Zhao W, Lau WB, Wang Y, Li Y, Du Y, Li L, Huang Y, Nie S, Qin Y, Ma X, Wei Y (2022) Extracellular vesicle-derived miR-144 as a novel mechanism for chronic intermittent hypoxia-induced endothelial dysfunction. Theranostics 12(9): 4237-4249. doi:10.7150/thno.69035

• Liu J, Zhang Y, Qu D, Zhang H, Wang L, Lau CW, Han JY, Pingcuo D, Huang Y & Liu L (2021) Salvianolic acid B ameliorates vascular endothelial dysfunction through the inhibition of bone morphogenetic protein 4 in diabetic mice. Life Sciences 286:120039.

• Zhang H, Dong J, Lau CW, Wei Y & Huang Y (2021) Berberine reverses nitroglycerin tolerance through suppressing PKCa activity in vascular smooth muscle cells. Cardiovascular Drugs and Therapy (Accepted)

• *Zhang H, Liu J, Qu D, Wang L, Wong CM, Lau CW, Huang Y, Wang YF, Huang H, Xia Y, Xiang L, Cai Z, Liu P, Wei Y, Yao X, Ma RCW & *Huang Y (2018) Serum exosomes mediate delivery of arginase 1 as a novel mechanism for endothelial dysfunction in diabetes. Proceedings of the Academy of National Sciences USA 115(29):E6927-E6936.

• Zhang H, Yang F, Guo Y, Wang L, Fang F, Wu H, Nie S, Wang Yifan, Fung ML, Huang Y, Deng H, Qin Y, Ma X & WeI Y (2018) The contribution of chronic intermittent hypoxia to OSAHS: from the perspective of serum extracellular microvesicle proteins. Metabolism – Clinical and Experimental 85(2018):97-108.

• Zhang H, Liu J, Qu D, Wang L, Luo JY, Lau CW, Liu P, Gao Z, Tipoe, GL, Lee HK, Ng CF, Ma RCW, Yao X & Huang Y (2016) Inhibition of miR-200c restores endothelial function in diabetic mice through suppression of COX-2. Diabetes 65(5):1196-1207 with Commentary Diabetes 65(5):1152-1154.

• Gao Z, Zhang H, Liu J, Lau CW, Liu P, Chen ZY, Lee HK, Tipoe GL, Ho HM, Yao X & Huang Y (2014) Cyclooxygenase-2-dependent oxidative stress mediates palmitate-induced impairment of endothelium-dependent relaxations in mouse arteries. Biochemical Pharmacology 91(4):474-481

• Leung SB, Zhang H, Lau CW, Huang Y & Lin Z (2013) Salidroside improves homocysteine induced endothelial dysfunction by reducing oxidative stress. Evidence-Based Complementary and Alternative Medicine 2013:679635, 8 pages