Dr Yang Zhang

PhD (2010-2013) Department of Physiology, Chinese University of Hong Kong, Hong Kong

Currently Postdoctoral Research Fellow at Brigham and Women's Hospital, Harvard Medical School, Boston, USA

• Luo JY, Cheng CK, Gou L, He L, Zhao L, Zhang Y, Wang L, Lau CW, Chen AF, Huang Y (2023) Induction of KLF2 by exercise activates eNOS to improve vasodilatation in diabetic mice. Diabetes 72(9):1330-1342.

• Chen H, Peng J, Wang T, Wen J, Chen S, Huang Y, Zhang Y (2023) Counter-regulatory renin-angiotensin system in hypertension: review and update in the era of COVID-19 pandemic. Biochemical Pharmacology 208 (2023):115370

• Wang C, Wu Y, Li Y, Zhang Y, Fung YK, Tong KK, Lau CW, Xiang L, Kwan KM, You LR, Huang Y, Tian XY (2023) Smad4-mediated angiogenesis facilitates beiging of white adipose tissue in mice. iScience 26(3):106272 (17 pages)

• Luo JY, Cheng CK, He L, Pu Y, Zhang Y, Lin X, Xu A, Lau CW, Tian XY, Ma RCW, Jo H & Huang Y (2022) Endothelial UCP2 is a mechanosensitive suppressor of atherosclerosis. Circulation Research 131(5):424-441.

• Leung FP, Yung LM, Ngai CY, Cheang WS, Tian XY, Lau CW, Zhang Y, Liu J, Chen ZY, Bian ZX, Yao X & Huang Y (2016) Chronic black tea consumption improves endothelial function in ovariectomized rats. European Journal of Nutrition 55(5):1963-1972.

• Hu W, Zhang Y, Wang L, Lau CW, Xu J, Luo JY, Gou L, Yao XY, Chen ZY, Ma RCW, Tian XY & Huang Y (2016) Bone morphogenic protein 4-Smad induced upregulation of platelet-derived growth factor AA impairs endothelial function. Arteriosclerosis, Thrombosis and Vascular Biology 36(3):553-560.

• Zhang Y, Liu J, Luo JY, Tian XY, Cheang WS, Xu J, Lau CW, Wang L, Wong WT, Wong CM, Lan HY, Yao XQ, Raizada MK & Huang Y (2015) Upregulation of angiotensin (1-7)-mediated signaling preserves endothelial function through reducing oxidative stress in diabetes. Antioxidants & Redox Signaling 23(11):880-892 with Cover Image of the Issue.

• Luo JY, Zhang Y, Wang L & Huang Y (2015) Regulators and effectors of BMP signaling in the cardiovascular system. The Journal of Physiology593(14):2995-3011

• Cheang WS, Ngai CY, Tam YY,  Tian XY, Wong WT, Zhang Y, Lau CW, Chen ZY, Bian ZX, Huang Y & Leung FP (2015) Black tea protects against hypertension-associated endothelial dysfunction through alleviation of endoplasmic reticulum stress. Scientific Reports 5:10340

• Liu J, Wang L, Tian XY, Liu LM, Wong WT, Zhang Y, Han Q, Ho HM, Wang N, Wong SL, Chen ZY, Yu J, Ng CF, Yao X & Huang Y (2014) Unconjugated bilirubin mediates heme oxygenase-1-induced vascular benefits in diabetic mice. Diabetes 64(5):1564-1577 with commentary 64(5):1506-1508.

• Wong CM, Zhang Y & Huang Y (2014) Bone morphogenic protein-4-induced oxidant signaling via protein carbonylation for endothelial dysfunction. Free Radical Biology and Medicine 75C:178-190

• Zhang Y, Liu J, Tian XY, Wong WT, Chen Y, Wang L, Luo JY, Cheang WS, Lau CW, Kwan KM, Wang N, Yao X & Huang Y (2014) Inhibition of bone morphogenic protein-4 restores endothelial function in db/db diabetic mice. Arteriosclerosis, Thrombosis and Vascular Biology 34(1):152-159

• Lau YS, Tian XY, Mustafa MR, Murugan D, Liu J, Zhang Y, Lau CW & Huang Y (2013) Boldine improves endothelial function in diabetic db/db mice through inhibiting angiotensin II-mediated BMP4 oxidative stress cascade. British Journal of Pharmacology 170(6):1190-1198

• Tian, XY, Wong WT, Xu A, Lu Y, Zhang Y, Wang L, Cheang WS, Wang Y, Yao X & Huang Y (2012) Uncoupling protein-2 protects endothelial dysfunction in diet-induced obese mice. Circulation Research 110:1211-1216.

• Tian XY, Wong WT, Leung FP, Zhang Y, Wang YX, Lee HK, Ng CF, Chen ZY, Yao X, Au CL, Lau CW, Vanhoutte PM, Cooke JP & Huang Y (2012) Oxidative stress-dependent cyclooxygenase-2-derived prostaglandin F2a impairs endothelial function in renovascular hypertensive rats Antioxidants & Redox Signaling 16(4):363-373.

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