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In this paper, we reconstitute a 3D osteogenic niche (3DON) mimicking that in bone marrow to support primary AML cell survival and phenotype maintenance in cultures. This is part of our complex organoid models technology.
Check out the published paper here: https://doi.org/10.1016/j.biomaterials.2024.122719
Dr. Nan Huang gave a seminar on July 3, 2024 in person and online on Zoom. His talk was on “Microfabrication of Programmable Cell Niche for Single Cell Study”.
In this paper, microarrays of protein-based 3D single cell micro-niche (3D-SCµN), with precisely engineered biophysical and biochemical niche signals, are micro-printed by our multiphoton microfabrication and micropatterning technology.
Check out the published paper here: https://doi.org/10.1016/j.biomaterials.2024.122684
