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In this paper, we investigated the role of RhoGTPases in the formation of compression-induced actin protrusions (CAPs) using mesenchymal stem cells encapsulated in 3D collagen micro-tissues.
Check out the published paper here: https://doi.org/10.1016/j.biomaterials.2021.120829
We used the multiphoton microfabrication and micropatterning (MMM) technology to engineer a spatially and quantitatively controllable bone morphogenetic protein-2 (BMP-2) soluble niche. The micropatterned NA bound-bBMP-2 niche elicited a more sustained and a higher level of the downstream Smad signaling than that by free BMP-2, in C2C12 cells.
Check out the published paper here: https://doi.org/10.1016/j.biomaterials.2020.120644
